![]() Both variants 2 and 3 encode the same isoform Cgrp. The resulting isoform (Cgrp) is shorter and has a distinct C-terminus, compared to isoform Calca. Status: REVIEWED Description Transcript Variant: This variant (3) has an altenate splice site in the 5' UTR, lacks the 3' terminal exon and has two alternate 3' exons, compared to variant 1. See identical proteins and their annotated locations for NP_001276373.1 ![]() NM_001289444.1 → NP_001276373.1 calcitonin gene-related peptide 1 isoform Cgrp preproprotein Location: 1 → 124 Calc_CGRP_IAPP Calcitonin / CGRP / IAPP family Status: REVIEWED Description Transcript Variant: This variant (2) lacks the 3' terminal exon and has two alternate 3' exons, compared to variant 1. See identical proteins and their annotated locations for NP_001029126.1 NM_001033954.3 → NP_001029126.1 calcitonin gene-related peptide 1 isoform Cgrp preproprotein This section to the one reported in Genomic regions, Identify version mismatches by comparing the version of the RefSeq in These reference sequences are curated independently of the genomeĪnnotation cycle, so their versions may not match the RefSeq versions in the current These reference sequences exist independently of genome builds. Expression Biased expression in CNS E11.5 (RPKM 1.9), cerebellum adult (RPKM 1.7) and 13 other tissues See more Orthologs human all NEW Try the new Gene table ![]() The human homolog of CGRP was found to have antimicrobial activity. CGRP can function as a vasodilator and play a role in the transmission of pain. Calcitonin and katacalcin modulate calcium levels in the blood stream. Post-translational processing of the calcitonin and CGRP propeptides results in either calcitonin and katacalcin, or CGRP, respectively. Alternative splicing of the mRNA results in multiple variants that encode either calcitonin or CGRP preproproteins. Full Name calcitonin/calcitonin-related polypeptide, alpha provided by MGI Primary source MGI:MGI:2151253 See related Ensembl:ENSMUSG00000030669 AllianceGenome:MGI:2151253 Gene type protein coding RefSeq status REVIEWED Organism Mus musculus Lineage Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Mus Mus Also known as CA Ct Ctn Calc Cgrp CGRP1 Calc1 CGRP-1 Summary This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide (CGRP) and katacalcin.
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